By Anshul V., Aditya N, and Rishab B.
Aging has been a marvel of scientific questions, one unanswered for many decades. People may wonder if it is ever possible to reverse the aging factor that controls all of life’s cycle. According to Harvard and MIT scientists, yes, it is possible.
In a new study, researchers say they have reversed aging in mice, and that discovery could set the stage for similar results in humans. Dr. David Sinclair has spent his entire career focused on aging and now believes he's discovered a way to stay younger for longer. Dr. Sinclair notes that reversing of aging could help prevent devastating diseases such as cancer, heart disease, diabetes, and Alzheimer's. Most importantly, the entire human race could boost age expectancy.
So how did these scientists actually accomplish this feat of science? It starts with a molecule called NAD+, also known as nicotinamide adenine dinucleotide, which humans use to live. As we get older, the level of NAD+ in our cells drops, leading to DNA damage and the diseases of aging. Scientists attempted to boost NAD levels in mice in order to reverse aging symptoms by putting doses of NAD+ into the water of a few mice. Instantly, the blood vessels were “young” again, increasing blood flow and nutrient delivery, helping to make the cells much more healthy which led to an overall efficient body system. Within the first week, the scientists saw age reversal in muscle and improvements in DNA repair.
Scientists have a capsule proxy called nicotinamide mononucleotide (NMN), also found in your daily greens, such as broccoli, cucumber, and avocados. This is changed into another compound that allows mice to produce more blood cells that line their muscles. Studies show mice improved their treadmill run time by an astonishing 60% compared to animals that did not get the molecule. The most impressive fact is that mice were able double their exercise endurance which matched the same endurance levels of young mice!
The ultimate goal of Dr. Sinclair's results is to see the feasibility on reversing age of human tissues. Currently, he has started a company in Boston, called MetroBiotech, to test the experiments, ethically, on humans. If his tests prove positive, Sinclair aims to use NAD+ to provision age-related damages on a much broader scale, such as shielding cancer patients from radiation treatments or protecting people from higher radiation work areas.
Most of all, it is important to realize that these futuristic technologies do not necessarily mean we should depend upon them so much that we forget to take care of ourselves. Reversed aging is for those who potentially need it to survive. Normal citizens should not use NAD+ doses for personal joy or alternatives. People should follow a healthy lifestyle and diet that will inevitably increase productivity and give an aesthetic health value.